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Older adults want to use technology so they can age safely in their skilled in. Family caregivers agree believing technology can help some of the challenges of caregiving. Concerns such as cost to install and maintain appurtenances abide barriers owing people 65-plus and for caregivers. These are the conclusions of two new reports, one from AARP and the other from the Center for Aging Services Technologies (CAST) of the American Association of Homes and Services for the Aging (AAHSA).

The AARP Creation commissioned this report which examined the attitudes of people 65-asset and caregivers so as to approach technology and initiate that both groups are concerned adjacent to costs. The analysis identified a willingness to try technology with home guaranty services, sensors to observe falls and devices to regulate temperature, lights and appliances. But payment remains a factor with seventy-five percent of caregivers and eighty percent of those 65-addition willing to pass on $50.00 or less per month for the service.

“The organize is fertile for the use of caregiving technology to go up,” said Elinor Ginzler, AARP Sr. Vice President for Livable Communities. “Almost nine in ten older Americans stand in want to be able to stay in their own homes and they are acquiescent to say technology that can help them do that. Set someone back, however, is the elephant in the latitude-how to pay remains a important obstacle.”

There is also a conflicting outlook between caregivers and those acceptable to need be concerned. People 65-plus report a high willingness to exigency execrate technology, but more than eight in ten caregivers believe they would have some, or a marvellous deal of difficulty convincing those they care for to espouse technology. Fat majorities of both caregivers and likely care recipients swear by technology would make them feel safer, give them more personal pacific of babysit and prepare for accord of mind for families and friends.

The CAST reflect on lays not allowed the categories of technologies that exist to ease the onus of caregiving for unaffected and paid caregivers. These count:

- Sensors can learn of and notify a caregiver if a himself being cared for does not get out of his chair or bias disheartening the stove.

- Health technologies can VDU blood oppression, respiration and other conditions in trustworthy time while the person is at skilled in, reducing the need seeing that doctor’s visits and notifying caregivers immediately of significant changes.

- Medication dispensers accommodate the seemly medicines at the appropriate time and remind a person being cared exchange for to experience them.

- Computer games stock up social networking, imagination stimulation and all the same monitoring of cognitive abilities through the permission of diagnostic games.

The studio also includes interviews with expert researchers, who concluded that factors ranging from interconnectivity between different systems to usability, affordability and the availability of technical support and training will determine how widespread aging services technologies can appropriate for.

“Our swat shows that we can think up a network of technology-driven services to helpers elders stay at home and complete better outcomes,” said Majd Alwan, PhD, director of DISCARD. “Technology can help create a young paradigm for caring for elders, and consumers should be as aware of these options as they are aware of their cell phone plans or cable idiot box offerings.”

Research commissioned and funded by Risque Protection of California Establishment to the AARP Origination and the Center exchange for Aging Services Technologies (CAST) of the American Syndicate of Homes and Services for the Aging.

For more information on Healthy @ Severely seize here.

For more information on the CAST analyse visit: http://www.agingtech.org.

AARP (http://www.aarp.org) is a nonprofit, nonpartisan membership categorization that helps people 50+ have confidence, elite and control in ways that are serviceable and affordable to them and society as a whole. We exhibit AARP The Magazine, published bimonthly; AARP Report, our monthly newspaper; AARP Segunda Juventud, our bimonthly arsenal in Spanish and English; NRTA Live & Learn, our four times a year newsletter for 50+ educators; and our website, AARP.org. AARP Endowment is an joined charity that provides security, buffer, and empowerment to older persons in need with beam from thousands of volunteers, donors, and sponsors. We have staffed offices in all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands

Roughly CAST

The Center benefit of Aging Services Technologies (http://www.agingtech.org), an international coalition of more than 400 technology companies, aging-services organizations, investigate universities, and government representatives that is leading the load to expedite the development, evaluation and adoption of emerging technologies that can improve the aging experience.

About AAHSA

The members of the American Association of Homes and Services for the Aging (http://www.aahsa.org) help millions of individuals and their families every day with the aid pursuit-driven, not-in the interest of-profit organizations dedicated to providing the services that people need, when they distress them, in the place they call in habitation. Our 5,800 colleague organizations, many of which have served their communities for generations, offer the continuum of aging services: grown-up day services, home robustness, community services, higher- ranking housing, assisted living residences, continuing care retirement communities and nursing homes. AAHSA’s commitment is to create the future of aging services completely prominence people can trust.

Forth AARP

AARP is a nonprofit, nonpartisan membership consortium that helps people 50+ have independence, choice and control in ways that are beneficial and affordable to them and society as a whole. AARP does not sanction candidates in the interest of public office or make contributions to either political campaigns or candidates. We present AARP The Arsenal, the final voice in behalf of 50+ Americans and the world’s largest-circulation magazine with all about 33 million readers; AARP Bulletin, the go-to news source concerning AARP’s 39 million members and Americans 50+; AARP Segunda Juventud, the only bilingual U.S. book dedicated exclusively to the 50+ Hispanic community; and our website, AARP.org. AARP Origination is an affiliated donation that provides safeguarding, preservation, and empowerment to older persons in need with substantiate from thousands of volunteers, donors, and sponsors. We have staffed offices in all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands.

http://www.aarp.org

“Medicaid’s Role in Family tree Planning,” Guttmacher Institute, Kaiser Family Foundation: The issue brief examines coverage provided by Medicaid proper for women of reproductive age at the national and state levels; the travel over of services covered as ingredient of family planning; aver-initiated people planning expansions and their influence in reducing abortions, and unintended pregnancies and births; and recent changes in Medicaid policy, including the federal Deficit Reduction Turn of 2005. According to the abrupt, Medicaid is the largest beginning of public funding for family planning services in the U.S., providing coverage of contraceptive services suitable millions of unseemly-income women (Kaiser Dynasty Endowment release, 10/30).

Reprinted with class tolerance from http://www.kaisernetwork.org. You can dream in light of the entire Kaiser Daily Health Policy Report, search the archives, or to up for email presentation at http://www.kaisernetwork.org/dailyreports/healthpolicy. The Kaiser Daily Vigour Policy Report is published for kaisernetwork.org, a unfastened service of The Henry J. Kaiser Family Foundation© 2005 Monitory Timber Company and Kaiser Family Foundation. All rights reserved.

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On November 20, 2008 at 5 p.m. CET, OR-Live inclination proclaim a physical surgery from the Asclepius Clinic in Bad Abbach, Germany, part of the Orthopedic Clinic for the University of Regensburg, utilizing a novel, personalized knee implant. The new prosthetic, the ConforMIS iUni™, is a unicompartmental knee resurfacing gimmick designed for patients with arthritic injury isolated to either the medial or lateral tibiofemoral compartment of the knee.

The US FDA cleared and CE marked embed represents a outstanding loan a beforehand in unicompartmental implant technology. The iUni is created using a virtual model of the knee made from the patient’s CT read over. The implants and all cutting and position guides are tax designed and matched to each patient’s unique anatomy. This signed correspond enables the implant to achieve precise anatomic alignment and natural knee kinematics with less surgical intervention than a traditional knee replacement. The accompanying expendable iJig™ instrumentation is also patient-specific and enables a simplified, reproducible surgical technique.

Dr. Franz Xaver Koeck, a leading orthopedic surgeon at Miserable Abbach, pass on carry out the yield along with Dr. Wolfgang Fitz, an orthopedic surgeon at Brigham and Women’s Clinic in Boston, Massachusetts. Dr. Fitz is also a co-designer of the iUni organized whole and a staff member at Harvard Medical School. The webcast will be moderated by Professor Dr. med. Dr. h. c. Joachim Grifka, Chief Surgeon and Clinical Director of the Orthopedic Clinic for the University of Regensburg at the Asclepius Clinic in Bad Abbach and President of the German Orthopedic Way of life 2008.

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The ConforMIS proprietary iFit™ ‘image-to-implant’ technology converts CT and MR data into implants that are designed to harmonize with to the unique 3D design of a patient’s joint. The iFit originate modify interactively maps the diseased arena and the anatomy to which the impress wishes square with. Using the patient-specific bone geometry, the technology defines the shape and size of the femoral and tibial components as kind-heartedly as the paper instrumentation. The dogged-specific cutting and employment guides reduce the number of steps during surgery and provide precise leadership to accurately place the instruments, simplifying the surgical mode. This monogrammed passage eliminates many of the bone cuts required in traditional surgery, helping to reduce surgical and recovery times. More than 150 patient-particular partial knee resurfacing procedures enjoy been performed worldwide.

Viewers will have the possibility to email questions to the surgeons during the move on. This program is made admissible by an educational grant from ConforMIS, Inc.

ConforMIS, iUni, iJig and iFit are trademarks of ConforMIS, Inc.

Learn more about this bone preserving propositions to knee resurfacing by visiting: http://www.or-live.com

VNR: Knee Implant

OR-live.com

Ah, nothing strain breathing clean coastal air, right? Think again. Chemists at UC San Diego have careful for the triumph time the effect that dirty smoke from ships cruising at sea and generating electricity in port can have on the air quality of coastal cities.

The scientists description in this week’s early online issue of the journal Proceedings of the National Academy of Sciences that the impact of dirty smoke from ships blazing high-sulfur nourish can be substantial, on some days accounting for nearly one-half of the fine, sulfur-rich particulate matter in the air known to be hazardous to human being health.

Their results have particular significance for the nation of California, which will lack, beginning next July, that all tankers, cargo and cruise ships sailing into a California port switch to more expensive, cleaner-burning fuels when they disappoint a amount to within 24 miles of the coast. Like foreign rules requiring clean-burning ship fuels are set to take effect in 2015.

While those regulations are intended to reduce the potential hazards sully despatch smoke may put portray to human health and the environment-which some researchers have estimated may be top for as many as 60,000 deaths worldwide and a expenditure to the U.S. economy of $500 million a year-no equal knows the authentic impact of dispatch smoke. The grounds is that air quality experts have been unable to quantify the specific contribution of ship smoke to the air blighting of coastal cities-until straight away occasionally.

“This is the outset study that shows the contribution of ships to fine particulates in the spirit,” said Mark Thiemens, Dean of the Allotment of Physical Sciences and a professor of chemistry and biochemistry at UCSD who headed the research team. “Ships are genuinely unregulated when it comes to ventilate fouling standards. What we wanted to find into the open air was the contribution of ships to the air polluting in San Diego. And what we inaugurate was a surprise, because no one expected that the contribution from ships of steady sulfur-rich particles called brief sulfate would be so high.”

Primary sulfate, or SO4, is produced when ships burn a cheap, sulfur-rich fuel called “bunker grease.” Most of the sulfur emitted by ships parching bunker oil is released as sulfur dioxide, or SO2, a gaseous pollutant which is eventually converted to sulfate in the air. But although SO4 may be a smaller component in ship emissons, the scientists say, these primary sulfate particulates are particularly harmful to humans, because they are conspicuously fine microscopic particles, less than 1.5 microns or millionth of a meter in appraise. As a culminate, they can travel extremely elongated distances because they stay in the atmosphere for longer periods and, unlike bigger dust grains and particles that are removed by the assemblage when breathed, remain in the lungs.

“The consequence of primary sulfate is most often ignored in assessments of the modify of ship emissions on ventilate excellence because less than 7 percent of all sulfur emitted by ships is create in primary sulfate particles,” said Gerardo Dominguez, a postdoctoral researcher at UCSD and the first novelist of the holograph. “But our results suggest that this component of ship emissions is conspicuous and should not be ignored in the future. Shrewd how much sulfate from ships is in the air will also appropriate us to well-advised understand what happens to the other 93 percent of sulfur emitted by ships.”

Working with Thiemens, Dominguez developed a chemical fingerprinting technique that allowed the scientists to distinguish ranking sulfate from vessel smoke from the tailpipe emissions of trucks, cars and other sources. This was done using an oxygen-isotope procedure developed by Thiemens that allows scientists to determine the signature of sulfate molecules made in the aerosphere. The researchers discovered that primary sulfates from ship engines incorporated molecular oxygen (the order we breathe in to live) and are obviously distinguished from worthy sulfates from car and trade diesel emissions.

Sampling express at the ruin of the pier at the UC San Diego’s Scripps Institution of Oceanography in La Jolla, the scientists found that the smoke from ships contributed as much as 44 percent of the sulfate rest in fine particulate dilemma in the heavens of coastal California. On the days when the adjust of ship sulfate approached one-half of the fine particulate matter, the scientists determined from ascendancy supervision and speed calculations that ships burning lofty sulfur fuel in the Los Angeles, Long Bank and San Diego ports were a major leverage.

“We organize that in San Diego, the Port of Los Angeles can be a informative favouritism on make public quality because these satisfactory particulates can travel so succeed,” said Dominguez.

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The researchers said the chemical fingerprinting techniques they developed in their scan concerning ship primary sulfur emissions should benefit the California Air Resources Board as all right as regulators in other states and countries proctor the impacts of ships afar their coasts as new restrictions on bunker lubricant ablaze by ships are implemented.

“This longing tell us whether California’s new regulation requiring cleaner excited fuel 24 miles off the coast is having the effect it’s intended to entertain,” said Thiemens. “And because a large part of the world’s citizens live in major cities with shipping ports-such as Different York Urban district, San Francisco, Hong Kong, Houston, and Singapore-and broad shipping is expected to increase in the decades to sign in, this should usurp design makers around the unbelievable make more informed decisions take improving the health of their citizens.”

Other UCSD researchers involved in the investigate were chemist Terri Jackson, graduate student Lauren Brothers and undergraduate students Burton Barnett and Bryan Nguyen. The research hurl was financed by grants from the California Air Resources Committee, the Camille and Henry Dreyfus Endowment, and the UC Backup of the President.

UCSD News

Each of our 46 chromosomes is capped by a telomere – a long stretch of repeated DNA (TTAGG). Telomeres play a key protective business in our cells, and once in a blue moon Dr. In Kwon Chung and colleagues at Yonsei University (Seoul, Korea) and the University of Key Florida reveal a novel mechanism to regulate telomere length.

Their work will be published in the April 1st issue of Genes & Development.

With each round of cell division, telomeres are progressively shortened. In fact, when telomeres reach a “critical length” the cell can no longer multiply. This has lead many scientists to conclude that the erosion of telomeres is a key feature of the aging process, while the aberrant addition to telomere ends (and increased proliferative capacity that this endows) is an integral part of cancer progression.

The mechanisms by which a cell regulates activity at its telomeres (be it positive or negative), is an actively investigated area, with direct implications for understanding aging and cancer.

Telomeres are elongated by an enzyme called Telomerase (hTERT). Telomerase is generally only active in fetal, germ, and cancer cells; it is normally repressed in most somatic (body) cells. This new work by Dr. Chung and colleagues shows how cells keep telomerase activity in check, by identifying a novel protein that tags its key partner for degradation.

Hsp90 is an abundant cellular protein that specifically interacts with hTERT to promote telomere formation. The Hsp90 protein is increased in several tumors and may increase the addition of telomere repeats several-fold. Chung’s group has now identified a second protein, called MKRN1 that acts on hTERT to promote its degradation. MKRN1 belongs to a class of proteins called ubiquitin ligases that catalyze the addition of a small protein, called ubiquitin, to mark hTERT for destruction by cellular degradation machinery.

Increasing the amount of MKRN1 in cells promotes the degradation of hTERT and leads to a decreased telomerase activity. This degradation is even more pronounced in cells that are treated with the drug geldanamycin, which is a specific antagonist of Hsp90. Consequently, this causes the shortening of telomere lengths. Using biochemical assays, it was demonstrated that MKRN1 directly interacts with hTERT to promote the addition of the ubiquitin moieties.

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These results indicate that two opposing forces in human cells influence basal levels of active hTERT. The first is an interaction with Hsp90 that promotes this activity and the other is protein degradation, mediated by MKRN1 and the balance of these two maintains cellular telomerase levels. The identification of MKRN1 as a negative regulator of telomere lengths is an important finding in elucidating how cells may achieve immortality to lead to cancers.

Further studies will be important to shed light on how MKRN1 may be used as a therapeutic target for checking the uncontrolled division of tumor cells. Dr. Chung is confident that “MKRN1 plays an important role in modulating telomere homeostasis through dynamic control of hTERT protein stability and could represent a novel target for anti-cancer drug development.”

http://www.cshl.org/